Pentobarbital will decrease the level or effect of methylprednisolone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. pentobarbital will decrease the level or effect of buspirone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Celador. pentobarbital will decrease the level or effect of nicardipine by affecting hepatic/intestinal enz... https://eduardobzvsq.blogsumer.com/29628102/la-regla-2-minuto-de-es-nembutal-un-barbitúrico